Mitochondria in lung biology and pathology: more than just a powerhouse

Mitochondria in lung biology and pathology: more than just a powerhouse.

An explosion of new information about mitochondria reveals that their importance extends well beyond their time-honored function as the "powerhouse of the cell." In this Perspectives article, we summarize new evidence showing that mitochondria are at the center of a reactive oxygen species (ROS)-dependent pathway governing the response to hypoxia and to mitochondrial quality control. The potent...

Mitochondria: More Than Just a Powerhouse

Pioneering biochemical studies have long forged the concept that the mitochondria are the 'energy powerhouse of the cell'. These studies, combined with the unique evolutionary origin of the mitochondria, led the way to decades of research focusing on the organelle as an essential, yet independent, functional component of the cell. Recently, however, our conceptual view of this isolated organell...

Mitochondria: More than Just “Power Plants” in Stem Cells

More than just vanilla.

More than just big ears

To the non-specialist, large ears in elephants used to mean African, small ears, Indian. But to taxonomists African elephants have long posed a more complex puzzle. During the nineteenth century, it was fashionable for wealthy trophy hunters to assign their own names to species they had shot destined for the museums of Europe. At least 18 elephant subspecies were claimed following this fashion....